When is testing indicated?

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Web Seminar: Pharmacogenetics in the Practice of Medicine

Pharmacogenetics tests are indicated primarily when a patient embarks on long-term therapy using a drug that has a narrow therapeutic index. A perfect example is coumadin (warfarin). Therapy can last for years; the effective range is very narrow; and dosing that wanders out of the safe and effective range can have severe consequences. There is little doubt that all patients embarking on long-term coumadin therapy should be tested.

The answer for other drugs is not so clear-cut, though there is an emerging body of evidence that suggests that those embarking on even relatively low-risk drug regimens would benefit from Pharmacogenetics (PGx) testing, since it would enable their physicians to anticipate differences in dose requirement or increased difficulty with drug interactions.

If you have a specific question about Pharmacogenetic testing indications, please contact us.