Periodontal Disease DNA Test
Identifies individuals with a 3 to 7 fold elevated risk of disease and tooth loss.

Consider testing if any of these statements apply to you:

• You're concerned about gum (periodontal) disease and want to know if you're at risk.
  
  
• You have early signs of periodontal disease.
  
  
• You have periodontal disease and want a personalized treatment plan based on your genetics.
  
  
• Your children may be at risk because you have gum disease.
  
  
• You may be at risk because a family member with gum disease.
  
  
• You're considering advanced surgical or complex restorative procedures such as implants.
  
  
• You're considering orthodontic treatment such as braces.
  

Periodontal Disease DNA testing identifies individuals who are genetically predisposed to severe periodontal disease. The risk for periodontal disease increases 3 to 7-fold and for tooth loss 3-fold in individuals who test positive.

Early detection of patients at increased risk facilitates prevention and early intervention efforts. For those patients already affected with periodontal disease, the PST™ Genetic Test assists clinicians in creating a personalized treatment plan.

Periodontal Disease, or gum disease, is a common condition that varies in severity from person to person and usually starts when people are in their 30's or 40's. Symptoms may include:

• red, swollen, tender gums
• bleeding while brushing and/or flossing
• receding gums
• loose or separating teeth
• persistent odorous breath
• dentures no longer fit
• pus between the teeth and gums
• a change in bite and jaw alignment

Periodontal Disease DNA testing or PST™ detects specific variations in the interleukin-1A and interleukin-1B genes.

The Testing Process

The process is simple. We send you a cheek swab collection kit in the mail. Samples are returned to our laboratory and results are typically available in 5-7 business days.

1. McGuire MK et al (1999). Prognosis versus the actual outcome. IV. The effectiveness of clinical parameters and the IL-1 genotype in accurately prognoses and tooth survival. J Periodontal 70:49-56.
2. Kornman KS et al (1997). The interleukin-1 genotype as a severity factor in adult periodontal diseases. J Clin Periodontal 24:72-77.
3. McDevitt MJ et al (2000). Interleukin-1 genetic assocaition with periodontis in clinical practice. J Periodontal 71:156-163.
4. Risk Assessment and the role of genetics in periodontal disease. (1999). Interleukin Genetic, Inc.