Periodontal Disease DNA Test

Identifies individuals with a 3 to 7 fold elevated risk of disease and tooth loss.

Consider testing if any of these statements apply to you:

• You're concerned about gum (periodontal) disease and want to know if you're at risk.
  
  
• You have early signs of periodontal disease.
  
  
• You have periodontal disease and want a personalized treatment plan based on your genetics.
  
  
• Your children may be at risk because you have gum disease.
  
  
• You may be at risk because a family member with gum disease.
  
  
• You're considering advanced surgical or complex restorative procedures such as implants.
  
  
• You're considering orthodontic treatment such as braces.
  

Periodontal Disease DNA testing identifies individuals who are genetically predisposed to severe periodontal disease. The risk for periodontal disease increases 3 to 7-fold and for tooth loss 3-fold in individuals who test positive.

Early detection of patients at increased risk facilitates prevention and early intervention efforts. For those patients already affected with periodontal disease, the PST™ Genetic Test assists clinicians in creating a personalized treatment plan.

Periodontal Disease, or gum disease, is a common condition that varies in severity from person to person and usually starts when people are in their 30's or 40's. Symptoms may include:

• red, swollen, tender gums
• bleeding while brushing and/or flossing
• receding gums
• loose or separating teeth
• persistent odorous breath
• dentures no longer fit
• pus between the teeth and gums
• a change in bite and jaw alignment

Periodontal Disease DNA testing or PST™ detects specific variations in the interleukin-1A and interleukin-1B genes.

The Testing Process

The process is simple. We send you a cheek swab collection kit in the mail. Samples are returned to our laboratory and results are typically available in 5-7 business days.

1. McGuire MK et al (1999). Prognosis versus the actual outcome. IV. The effectiveness of clinical parameters and the IL-1 genotype in accurately prognoses and tooth survival. J Periodontal 70:49-56.
2. Kornman KS et al (1997). The interleukin-1 genotype as a severity factor in adult periodontal diseases. J Clin Periodontal 24:72-77.
3. McDevitt MJ et al (2000). Interleukin-1 genetic assocaition with periodontis in clinical practice. J Periodontal 71:156-163.
4. Risk Assessment and the role of genetics in periodontal disease. (1999). Interleukin Genetic, Inc.

Disclaimer

The content of this web site is for public use, free of charge, and for information only. It is not intended to be used in any other way. The authors disclaim any liability, loss, injury, or damage incurred as a consequence, directly or indirectly, of the use and application of any of the content of this web site.

The information presented on this site is intended as general health information and as an educational tool. It is not intended as medical advice. Only a physician, pharmacist, or other healthcare professional should advise a patient on medical issues and should do so using a medical history and other factors identified and documented as part of the health professional/patient relationship.