Has Strattera caused you to have side effects or adverse drug
reactions?
Do you have a long history of reactions to medications?
Is your physician thinking of prescribing Strattera?
Are you
concerned about Drug Sensitivity?
If you answered yes to any of these questions, you should ask your healthcare provider about DNA Drug Sensitivity Testing™ from Genelex.
Strattera is a non-stimulant medication known as a norepinephrine
reuptake inhibitor used for the treatment of attention-deficit/hyperactivity
disorder (ADD and ADHD). Although the FDA has approved the drug, the current FDA-approved Strattera label states
"Poor metabolizers of CYP2D6 have a 10–fold higher AUC and a 5–fold higher peak concentration to a given dose of STRATTERA compared with extensive metabolizers (click here to learn more about the review process).
Strattera is one of many medications processed through
pathways in your liver. These pathways vary in their ability
to process drugs based on your unique genetic make-up. A fraction of the population
(about 7% of Caucasians and 2% of African-Americans) are poor
metabolizers (PMs) of CYP2D6 metabolized drugs.
Now your healthcare provider can help optimize your response to Strattera and many other medications by ordering DNA testing. Your results will be entered into our personalized medication management software, GeneMedRx You or your healthcare providers can log in to see if current or future medications are predicted to cause drug-drug or drug-gene interactions so dosage and selection can be catered to your needs. You receive a 90-day subscription free with your testing; additional one year extensions are available for a nominal fee. Of course, your DNA never changes so the testing only needs to be done once in a lifetime.
Click here to view a list of drugs for which DNA testing may be helpful.
The Testing Process
The process is simple. You can order testing directly if you have a physician prescription or your healthcare provider can request testing for you. We send a cheek swab collection kit with directions by mail. Samples are submitted using the enclosed return mailer and results are provided in ten days or less. Faster testing is available for an additional charge. Call a DNA testing consultant at (800) 523-3080 for details and to order, or request information to you or to your healthcare provider on your behalf, simply complete the request form.
References
http://www.medscape.com/viewarticle/508543_2
Oesterheld, Jessica, M.D. GeneMedRx Drug Metabolism Tables
http://www.ncbi.nlm.nih.gov/pubmed/9555760
http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021411s029s030lbl.pdf
Note: Testing requires a prescription from a physician.
Disclaimer: Do not alter the dosage amount or schedule of any drug you are taking without first consulting a qualified healthcare professional.
The text presented on this page is not a substitute for professional medical advice. It is for your information only and may not represent your true individual medical situation. Do not hesitate to consult your healthcare provider if you have any questions or concerns.
Unless provided information expressly states that is was created by an MD or PharmD or cites another specific source, it was authored by Genelex employees that are not healthcare providers.
By Kristine Ashcraft, B.S. Last Reviewed 7/30/10
